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When implementing define.xml as part of a clinical trial study data submission package, which section is pivotal for explaining algorithmic derivations and handling of special data scenarios to a regulatory reviewer?

You are tasked with producing a series of Forest plots to graphically display the results of a subgroup analysis in a clinical study using PROC SGPLOT. You must alter the marker attributes for each subgroup to enhance the clarity of the plot. Which combination of statements and options should you use to modify the marker color, size, and style for each subgroup's reference line, within the context of PROC SGPLOT?

A clinical trials programmer is tasked with creating a Kaplan-Meier survival plot with a log-rank test for comparing survival curves between two treatment groups. The dataset includes patient ID, treatment group, time to event or censor, and the event indicator. Which PROC step will they likely use to produce the required output?

During a clinical trial data analysis, you intend to use a SAS automatic variable that contains the current date whenever the SAS code is executed. This will be utilized to flag all records from the clinical trial data set that have been captured after a certain cutoff date. Which of the following SAS automatic variables should be used to get the current date in a data step?

You are working on a clinical trial data set in SAS, and you need to create a new variable that captures the number of days since the start of the study. The study start date is available as an automatic variable called `Study_Start_Date`, and each patient's visit date is recorded in a variable called `Visit_Date`. Which of the following code snippets correctly calculates the new variable `Days_Since_Start`?