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Exam Code: MCAT
Exam Questions: 815
Medical College Admission Test: Verbal Reasoning, Biological Sciences, Physical Sciences, Writing Sample
Updated: 24 Aug, 2026
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Question 1

At a recent meeting of the American Public Transit Association, the Environmental Protection Agency unveiled
stringent new standards for pollution control. The transit authorities were particularly concerned about the
implementation of a proposed “Clean Air Act.” They believed the provisions of the Clean Air Act could severely
affect basic services to their local communities. Many transit agencies were concerned that it would be difficult
to comply with the pollution and emissions control standards while continuing to operate within realistic budgets.
The aim of the Clean Air Act is to assure that by the year 2000, there will be a reduction of at least 10 million
tons of sulfur dioxide from 1980 levels. The bill also calls for a reduction in pollutants that contribute to the
depletion of ozone. Strict regulations of toxic air emissions would have to be established and enforced.
Additionally, the Clean Air Act would establish specific acid-rain reduction quotas and enforce severe penalties
for transgressors of any of the new clean air regulations.
There is little doubt that mass-transit suppliers will be considerably affected by this new legislation, just as the
chemical and petroleum industries have already been affected by similar legislation. Transit authorities are
challenged to strike a difficult balance between complying with the government’s new standards and developing
an official concern for the environment, while continuing to fulfill the transportation needs of the general
population.
Among the areas addressed by the Clean Air Act, the topic of mobile resources is of particular interest to mass
transit authorities. Provisions contained in the Act under this title are aimed at encouraging the development
and practical use of alternative fuel sources, like solar energy and methane fuel. The goal of this section of the
Act is to eradicate toxic fuel emissions in order to provide cleaner air and a more favorable environment. The
Act even goes so far as to declare that in cities like New York, Los Angeles and Houston – where air quality is
particularly noxious and toxins exceed the limits of federal regulations – forms of mass transit should run on socalled “clean-burning fuels” by the year 2000. Such fuels include reformulated gasoline, propane, electricity,
natural gas, ethanol, methanol, or any similar type of low-emission fuel. In addition, the Act proposes that, by
1994, all new urban buses in cities with populations exceeding one million must operate solely on clean-burning
fuels.
The topics of alternative fuels and alternative fuel vehicles represent, by far, the most controversial issue in the
Clean Air Act. President Bush has called alternative fuels “bold and innovative” means to control pollution, but
according to many transportation experts, the Act’s proposals on alternative fuel usage are unrealistic. The
transit authorities recognize that concern for the environment and health hazards like pollution are global
issues. However, most transit officials concur that inventing and developing new ways to fuel mass transit will
take at least 50 years to realize. They point out that the Act does not mention the political and social
ramifications of usurping the role of the petroleum industries. The Act does not mention if or how the thousands
of people employed by the oil industry will get retrained to produce and implement the use of “clean” fuel.
No one disputes the fact that people need some form of transportation to get from place to place. Preserving
the environment should be a priority, yet we need to remember that even if toxic emissions are completely
eliminated sometime in the future, the challenge of moving mass numbers of people where they want to go will
still exist and must remain a priority. Transit authorities contend that unless the Clean Air Act also
acknowledges this, and develops a way to encourage mass transit over personal transportation, the problems
of pollution might not be significantly altered. They suggest that there are many areas in this country that have
little or no mass transit and that, if the Clean Air Act’s goal is to reduce pollution, perhaps the most practical and
realistic means to achieve that goal is to encourage the development and maintenance of mass transit
systems.
The main goal of the “Mobile Resources” section of the Clean Air Act is to:

Section: Verbal Reasoning

Options :
Answer: A

Question 2

…Until last year many people – but not most economists – thought that the economic data told a simple tale.
On one side, productivity – the average output of an average worker – was rising. And although the rate of
productivity increase was very slow during the 1970’s and early 1980’s, the official numbers said that it had
accelerated significantly in the 1990’s. By 1994 an average worker was producing about 20 percent more than
his or her counterpart in 1978.
On the other hand, other statistics said that real, inflation- adjusted wages had not been rising at anything like
the same rate. In fact, some of the most commonly cited numbers showed real wages actually falling over the
last 25 years. Those who did their homework knew that the gloomiest numbers overstated the case…Still, even
the most optimistic measure, the total hourly compensation of the average worker, rose only 3 percent between
1978 and 1994…
…But now the experts are telling us that the whole thing may have been a figment of our statistical
imaginations… a blue-ribbon panel of economists headed by Michael Boskin of Stanford declared that the
Consumer Price Index [C.P.I.] had been systematically overstating inflation, probably by more than 1 percent
per year for the last two decades, mainly failing to take account of changes in the patterns of consumption and
improvements in product quality…
…The Boskin report, in particular, is not an official document – it will be quite a while before the Government
actually issues a revised C.P.I., and the eventual revision may be smaller than Boskin and his colleagues
propose. Still, the general outline of the resolution is pretty clear. When all the revisions are taken into account,
productivity growth will probably look somewhat higher than it did before, because some of the revisions being
proposed to the way we measure consumer prices will also affect the way we calculate growth. But the rate of
growth of real wages will look much higher – and so it will now be roughly in line with productivity, which will
therefore reconcile numbers on productivity and wages with data that show a roughly unchanged distribution of
income between capital and labor. In other words, the whole story about workers not sharing in productivity
gains will turn out to have been based on a statistical illusion.
It is important not to go overboard on this point. There are real problems in America, and our previous concerns
were by no means pure hypochondria. For one thing, it remains true that the rate of economic progress over
the past 25 years has been much slower than it was in the previous 25. Even if Boskin’s numbers are right, the
income of the median family – which officially has experienced virtually no gain since 1973 – has risen by only
about 35 percent over the past 25 years, compared with 100 percent over the previous 25. Furthermore, it is
quite likely that if we “Boskinized” the old data – that is, if we tried to adjust the C.P.I. for the 50’s and 60’s to
take account of changing consumption patterns and rising product quality – we would find that official numbers
understated the rate of progress just as much if not more than they did in recent decades…
…Moreover, while workers as a group have shared fully in national productivity gains, they have not done so
equally. The overwhelming evidence of a huge increase in income inequality in America has nothing to do with
price indexes and is therefore unaffected by recent statistical revelations. It is still true that families in the
bottom fifth, who had 5.4 percent of total income in 1970, had only 4.2 percent in 1994; and that over the same
period the share of the top 5 percent went from 15.6 to 20.1. And it is still true that corporate C.E.O.’s, who
used to make about 35 times as much as their employees, now make 120 times as much or more…
…While these are real and serious problems, however, one thing is now clear: the truth about what is
happening in America is more subtle than the simplistic morality play about greedy capitalists and oppressed
workers that so many would-be sophisticates accepted only a few months ago. There was little excuse for
buying into that simplistic view then; there is no excuse now…
The Boskin report does all of the following EXCEPT:

Section: Verbal Reasoning

Options :
Answer: C

Question 3

Several techniques have been developed to determine the order of a reaction. The rate of a reaction cannot be
predicted on the basis of the overall equation, but can be predicted on the basis of the rate-determining step.
For instance, the following reaction can be broken down into three steps.
A + D → F + G
Step 1
A → B + C
(slow)
Step 2
B + D → E + F
(fast)
Step 3
E + C → G
(fast)
Reaction 1
In this case, the first step in the reaction pathway is the rate-determining step. Therefore, the overall rate of the
reaction must equal the rate of the first step, k1 [A] where k1 is the rate constant for the first step. (Rate
constants of the different steps are denoted by kx
, where x is the step number.)
In some cases, it is desirable to measure the rate of a reaction in relation to only one species. In a secondorder reaction, for instance, a large excess of one species is included in the reaction vessel. Since a relatively
small amount of this large concentration is reacted, we assume that the concentration essentially remains
unchanged. Such a reaction is called a pseudo first-order reaction. A new rate constant, k', is established, equal
to the product of the rate constant of the original reaction, k, and the concentration of the species in excess.
This approach is often used to analyze enzyme activity.
In some cases, the reaction rate may be dependent on the concentration of a short-lived intermediate. This can
happen if the rate-determining step is not the first step. In this case, the concentration of the intermediate must
be derived from the equilibrium constant of the preceding step. For redox reactions, the equilibrium can be
correlated with the voltage produced by two half-cells by means of the Nernst equation. This equation states
that at any given moment:
MCAT-part-3-page300-image146
Equation 1
When
a A + b B → c C + d D
Reaction 2
Note: R = 8.314 J/K·mol; F = 9.6485 × 104 C/mol.)
Catalysts are effective in increasing the rate of a reaction because they:

Section: Physical Sciences

Options :
Answer: D

Question 4

In an acetyl molecule, two atoms of carbon are bonded by: 


Section: Physical Sciences 

Options :
Answer: D

Question 5

Nitric oxide, NO, has recently been found to have widespread physiological effects, acting as a major regulator
in the nervous, cardiovascular, and immune systems. The production of NO in the body is regulated by specific
NOS enzymes which exist in at least three different isoforms – bNOS, eNOS, and macNOS. Each of these
isoforms differ in location and function and serve to mediate different physiological responses to NO. Some
physiological roles of NO have been demonstrated as follows:
I. In the central nervous system, NO production is regulated by bNOS. Calcium ion concentrations of 200-400
nM in the central nervous system activate bNOS to catalyze the formation of NO. NO exerts definite effects on
brain function although its specific roles are not well established. bNOS inhibitors have been found to block the
release of neurotransmitter from presynaptic neurons. Excess levels of NO are also thought to contribute to
neurodegenerative disorders such as Alzheimer’s disease.
II. In the blood vessels, NO is produced by eNOS which is activated by Ca2+ concentrations of 200-400 nM. NO
acts as the major endogenous vasodilator in blood vessels. It diffuses into smooth muscle cells and leads to
muscle relaxation by stimulating cGMP formation through activation of guanylyl cyclase. In addition, NO
regulates the vascular system by inhibiting platelet aggregation and adhesion.
III. The role of NO in the immune system is regulated by macNOS through a pathway that is not Ca2+
dependent. Rather, exposure to cytokines, including interleukin-1 and interferon- γ, leads to synthesis of large
amounts of NO by activation of macNOS in response to inflammatory stimuli. The NO produced plays a
definitive role in the mediation of the activities of macrophages and neutrophils. NO also acts to inhibit the
mechanism of viral replication.
A “knock out” mouse with a mutant bNOS protein was generated by recombination techniques. The mutant
protein was identical to the wild-type protein except for the identity of amino acid 675; the mutated bNOS has
Tryptophan instead of Cysteine at position 675. Which of the following is responsible for the mutant protein?

Section: Biological Sciences 

Options :
Answer: C

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