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Question 1

Select the class of Anti-diabetic medication that works in the specified organ to prevent hyperglycemia.

Select all that applies. Liver (D)

Options :

A : Sulfonylureas

B : Alpha- Glucosidase Inhibitors

C : DPP4 Inhibitors

D : Glucagon-like peptide-1 receptor agonists

E : Thiazolidinediones

F : Biguanide

G : SGLT2 inhibitors

Answer: C

Question 2

Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a

Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP

component) divided q6h.

How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single

dose? Patient weighs 80kg.

Options :

A : 18.75 mL

B : 75 mL

C : 15 mL

D : 50 mL

E : 16.5 mL

Answer: A

Question 3

Which of the following medication can lower seizures threshold?

Options :

A : Bupropion

B : Tramadol

C : Clozapine

D : Thiothixene

E : All of the above can lower seizure threshold

Answer: A

Question 4

Which of the following would be most appropriate to treat stenotrophomonas maltophilia?

Options :

A : Meropenem

B : Vancomycin

C : Ciprofloxacin

D : Sulfamethoxazole/trimethoprim

E : Cefepime

Answer: D

Question 5

Which of the following statements is true regarding Drug-receptor bonds?

Options :

A : Covalent bonds of drugs with receptors are strong and mostly reversible

B : Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions

C : Electrostatic bonds are stronger than covalent bonds

D : Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes

E : Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond

Answer: A